Lux Radio Theater, a long-run classic radio anthology series (NBC Blue Network (1934-1935); CBS (1935-1954); NBC (1954-1955)) which first adapted Broadway stage works, and then films to hour-long live radio presentations. It became the most popular dramatic anthology series on radio, broadcast for more than 20 years, and continued on television as the Lux Video Theatre through most of the 1950s.

Cecil B. DeMille was the host of the series each Monday evening from June 1, 1936, until January 22, 1945. On several occasions, usually when he was out of town, he was temporarily replaced by various celebrities, including Leslie Howard and Edward Arnold .

Lux Radio Theater strove to feature as many of the original stars of the original stage and film productions as possible, usually paying them $5,000 an appearance. In 1936, when sponsor Lever Brothers (who made Lux soap and detergent) moved the show from New York City to Hollywood, the program began to emphasize adaptations of films rather than plays. The first Lux film adaptation was The Legionnaire and the Lady, with Marlene Dietrich and Clark Gable, based on the film Morocco. That was followed by a Lux adaptation of The Thin Man, featuring the movie's stars, Myrna Loy and William Powell.

Many of leading names in stage and film appeared in the series, most in the roles they made famous on the screen, including Abbott and Costello, Jean Arthur, Lauren Bacall, Lucille Ball, Ethel Barrymore, John Barrymore, Lionel Barrymore, Ingrid Bergman, Humphrey Bogart, Charles Boyer, James Cagney, Claudette Colbert, Ronald Colman, Gary Cooper, Joseph Cotten, Joan Crawford, Bing Crosby, Bette Davis, Dan Duryea, Frances Farmer, Errol Flynn, Ava Gardner, Judy Garland,Greer Garson, Cary Grant, Lillian Gish, Charlton Heston, Bob Hope, Vivien Leigh, Fredric March,Agnes Moorehead, Paul Muni, Vincent Price, Donna Reed, Ginger Rogers, Mickey Rooney, Frank Sinatra, Ann Sothern, Barbara Stanwyck, James Stewart, Shirley Temple, Gene Tierney, Spencer Tracy, Lana Turner, John Wayne, Jane Wyman, Orson Welles, Loretta Young and Robert Young.

Radio regulars: Though the show focused on film and its performers, perhaps inevitably several classic radio regulars appeared in Lux Radio Theater productions. Jim and Marian Jordan, better known as Fibber McGee and Molly, appeared on the show twice and also built an episode of their own radio comedy series around one of those appearances. Their longtime costar, Arthur Q. Bryan (wisecracking Doc Gamble) made a few Lux appearances as well. Bandleader Phil Harris, a longtime regular on Jack Benny's radio program, and his wife Alice Faye, who became radio stars with their own comedy show in 1948, appeared in a Lux presentation. Fred Allen, Jack Benny (with and without his wife, Mary Livingstone), George Burns and Gracie Allen were among the other radio stars who were invited to do Lux presentations as well.

 Advertisement featuring Joan CrawfordAt least once Lux Radio Theater presented an adaptation of the film version of a radio series, The Life of Riley, featuring William Bendix as the Brooklyn-born, California-transplanted, stumbling but bighearted aircraft worker he already made famous in the long-running radio series (and eventual television hit) of the same name.

But also at least once Lux Radio Theater offered a presentation without any known performers---its adaptation of This Is the Army during World War II featured a cast of American soldiers.

Mercury Theatre on the Air — which eventually made Orson Welles a force to be reckoned with, especially with his broadcast of The War of the Worlds (30 October 1938) provoked — was initially a summer replacement series for Lux Radio Theater in 1938.

A famous urban legend claimed that actor Sonny Tufts was slated to appear as a guest alongside Joan Fontaine for a production of The Major and the Minor on Lux Radio Theater. When Joseph Cotton read the names of the next week's cast, he supposedly said, with a mixture of shock and astonishment, that listeners would hear "that new, talented personality... Sonny Tufts?!" However, this never happened. The legend began as a fake segment on one of Kermit Shafer's popular "Bloopers" albums, which have been criticized for their "re-creations", fabrications and lack of accuracy. In actuality, Tufts was introduced by Cotton on the radio series Suspense, but Cotton's introduction was perfectly normal.